ID   1.3.98.3
DE   coproporphyrinogen dehydrogenase.
AN   coproporphyrinogen III oxidase.
AN   oxygen-independent coproporphyrinogen-III oxidase.
CA   coproporphyrinogen III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine
CA   + 2 CO2 + 2 L-methionine + protoporphyrinogen IX.
CC   -!- Differs from EC 1.3.3.3 by using S-adenosyl-L-methionine (AdoMet)
CC       instead of oxygen as oxidant.
CC   -!- Occurs mainly in bacteria, whereas eukaryotes use the oxygen-
CC       dependent oxidase.
CC   -!- The reaction starts by using an electron from the reduced form of the
CC       enzyme's [4Fe-4S] cluster to split AdoMet into methionine and the
CC       radical 5'-deoxyadenosin-5'-yl; this radical initiates attack on the
CC       2-carboxyethyl groups, leading to their conversion into vinyl groups.
CC   -!- This conversion, -.CH-CH2-COO- -> -CH=CH2 + CO2 + e(-) replaces the
CC       electron initially used.
CC   -!- Formerly EC 1.3.99.22.
DR   P33770, HEMF_CERS4 ;  O67886, HEMN_AQUAE ;  O31381, HEMN_BRADU ;
DR   P51008, HEMN_CERS4 ;  P95651, HEMN_CERS5 ;  O34162, HEMN_CUPNH ;
DR   P32131, HEMN_ECOLI ;  Q9ZLH0, HEMN_HELPJ ;  O25376, HEMN_HELPY ;
DR   P95506, HEMN_MANHA ;  Q51676, HEMN_PARDP ;  P77915, HEMN_PSEAE ;
DR   P0A1E2, HEMN_SALTI ;  P0A1E1, HEMN_SALTY ;  P74132, HEMN_SYNY3 ;
DR   O31067, HEMN_THEVL ;
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