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ENZYME entry: EC 1.3.98.5

Accepted Name
Hydrogen peroxide-dependent heme synthase.
Alternative Name(s)
Coproheme III oxidative decarboxylase.
Reaction catalysed
Fe-coproporphyrin III + 2 H(2)O(2) <=> protoheme + 2 CO(2) + 4 H(2)O
Comment(s)
  • The enzyme participates in a heme biosynthesis pathway found in Gram- positive bacteria.
  • The initial decarboxylation step is fast and yields the three- propanoate harderoheme isomer III.
  • The second decarboxylation is much slower, cf. EC 1.3.98.6.
Cross-references
BRENDA1.3.98.5
EC2PDB1.3.98.5
ExplorEnz1.3.98.5
PRIAM enzyme-specific profiles1.3.98.5
KEGG Ligand Database for Enzyme Nomenclature1.3.98.5
IUBMB Enzyme Nomenclature1.3.98.5
IntEnz1.3.98.5
MEDLINEFind literature relating to 1.3.98.5
MetaCyc1.3.98.5

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