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ENZYME entry: EC 1.3.99.18

Accepted Name
quinaldate 4-oxidoreductase.
Alternative Name(s)
quinaldic acid 4-oxidoreductase.
Reaction catalysed
A + H2O + quinaldate <=> AH2 + kynurenate
Comment(s)
  • The enzyme from Pseudomonas sp. AK2 also acts on quinoline-8- carboxylate, whereas that from Serratia marcescens 2CC-1 will oxidize nicotinate; quinaldate is a substrate for both of these enzymes.
  • 2,4,6-Trinitrobenzene sulfonate acid, 1,4-benzoquinone, 1,2- naphthoquinone, nitroblue tetrazolium (NBT), thionine and menadione will serve as an electron acceptor for the former enzyme and ferricyanide for the latter; Meldola blue, iodonitrotetrazolium chloride (INT), phenazine methosulfate (PMS), 2,6- dichlorophenolindophenol (DCPIP) and cytochrome c will act as electron acceptors for both.
Cross-references
BRENDA1.3.99.18
EC2PDB1.3.99.18
ExplorEnz1.3.99.18
PRIAM enzyme-specific profiles1.3.99.18
KEGG Ligand Database for Enzyme Nomenclature1.3.99.18
IUBMB Enzyme Nomenclature1.3.99.18
IntEnz1.3.99.18
MEDLINEFind literature relating to 1.3.99.18
MetaCyc1.3.99.18
Rhea expert-curated reactions1.3.99.18

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