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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
1-hydroxycarotenoid 3,4-desaturase.
Alternative Name(s)
1-hydroxycarotenoid 3,4-dehydrogenase.
Carotenoid 3,4-dehydrogenase.
Hydroxyneurosporene desaturase.
Reaction catalysed
1-hydroxy-1,2-dihydrolycopene + acceptor <=> 1-hydroxy-3,4-didehydro-1,2-dihydrolycopene + reduced acceptor
  • The enzymes from Rubrivivax gelatinosus and Rhodobacter sphaeroides prefer the acyclic carotenoids (e.g. 1-hydroxy-1,2- dihydroneurosporene, 1-hydroxy-1,2-dihydrolycopene) as substrates.
  • The conversion rate for the 3,4-desaturation of the monocyclic 1'-hydroxy-1',2'-dihydro-gamma-carotene is lower.
  • The enzyme from the marine bacterium strain P99-3 shows high activity with the monocyclic carotenoid 1'-hydroxy-1',2'-dihydro-gamma- carotene.
  • The enzyme from Rhodobacter sphaeroides utilizes molecular oxygen as the electron acceptor in vitro.
  • However, oxygen is unlikely to be the natural electron acceptor under anaerobic conditions.
PRIAM enzyme-specific profiles1.3.99.27
KEGG Ligand Database for Enzyme Nomenclature1.3.99.27
IUBMB Enzyme Nomenclature1.3.99.27
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