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ENZYME

ENZYME entry: EC 1.4.1.14

PURL: https://purl.expasy.org/enzyme/EC/1.4.1.14
Accepted Name
glutamate synthase (NADH)
Alternative Name(s)
L-glutamate synthase
L-glutamate synthetase
NADH-dependent glutamate synthase
NADH-glutamate synthase
Reaction catalysed
2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)
Comment(s)
  • A flavoprotein (FMN).
  • The reaction takes place in the direction of L-glutamate production.
  • The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2).
Cross-references
BRENDA1.4.1.14
EC2PDB1.4.1.14
ExplorEnz1.4.1.14
KEGG Ligand Database for Enzyme Nomenclature1.4.1.14
IUBMB Enzyme Nomenclature1.4.1.14
MEDLINEFind literature relating to 1.4.1.14
MetaCyc1.4.1.14
Rhea expert-curated reactions1.4.1.14
UniProtKB/Swiss-Prot
Q03460, GLSN_MEDSAQ0JKD0, GLT1_ORYSJQ9C102, GLT1_SCHPO
Q12680, GLT1_YEASTQ0DG35, GLT2_ORYSJQ9LV03, GLUT1_ARATH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-