Expasy logo

ENZYME

ENZYME entry: EC 1.4.1.18

PURL: https://purl.expasy.org/enzyme/EC/1.4.1.18
Accepted Name
lysine 6-dehydrogenase
Alternative Name(s)
L-lysine 6-dehydrogenase
L-lysine epsilon-dehydrogenase
LysDH
Reaction catalysed
L-lysine + NAD(+) = L-1-piperideine-6-carboxylate + NH4(+) + NADH + 2 H(+)
Comment(s)
  • Highly specific for L-lysine as substrate, although (S)- (2-aminoethyl)-L-cysteine can act as a substrate, but more slowly.
  • While the enzyme from Agrobacterium tumefaciens can use only NAD(+), that from the thermophilic bacterium Geobacillus stearothermophilus can also use NADP(+), but more slowly.
Cross-references
BRENDA1.4.1.18
EC2PDB1.4.1.18
ExplorEnz1.4.1.18
KEGG Ligand Database for Enzyme Nomenclature1.4.1.18
IUBMB Enzyme Nomenclature1.4.1.18
MEDLINEFind literature relating to 1.4.1.18
MetaCyc1.4.1.18
Rhea expert-curated reactions1.4.1.18
UniProtKB/Swiss-Prot
Q9AJC6, LYSDH_GEOSE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-