Expasy logo

ENZYME

ENZYME entry: EC 1.4.2.2

PURL: https://purl.expasy.org/enzyme/EC/1.4.2.2
Accepted Name
nicotine dehydrogenase
Reaction catalysed
(S)-nicotine + 2 Fe(III)-[cytochrome c] = N-methylmyosmine + 2 Fe(II)-[cytochrome c] + 2 H(+)
Comment(s)
  • The enzyme, characterized from the bacterium Pseudomonas putida S16, contains an FAD cofactor and belongs to the flavin-containing amine oxidase family.
  • The enzyme from this bacterium is specific for the c-type cytochrome CycN.
  • The product undergoes spontaneous hydrolysis to form pseudooxynicotine.
Cross-references
BRENDA1.4.2.2
EC2PDB1.4.2.2
ExplorEnz1.4.2.2
KEGG Ligand Database for Enzyme Nomenclature1.4.2.2
IUBMB Enzyme Nomenclature1.4.2.2
MEDLINEFind literature relating to 1.4.2.2
MetaCyc1.4.2.2
Rhea expert-curated reactions1.4.2.2
UniProtKB/Swiss-Prot
F8G0P2, NICA2_PSEP6

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-