ENZYME entry: EC 1.4.3.23
Accepted Name |
7-chloro-L-tryptophan oxidase.
|
Reaction catalysed |
7-chloro-L-tryptophan + O(2) <=> 2-imino-3-(7-chloroindol-3-yl)propanoate + H(2)O(2) |
Comment(s) |
- This enzyme catalyzes a step in the biosynthesis of rebeccamycin,
an indolocarbazole alkaloid produced by the bacterium Lechevalieria
aerocolonigenes.
- During catalysis, the bound FAD is reoxidized at the expense of
molecular oxygen, producing one molecule of hydrogen peroxide.
- The enzyme shows significant preference for 7-chloro-L-tryptophan
over L-tryptophan.
|
Cross-references |
BRENDA | 1.4.3.23 |
EC2PDB | 1.4.3.23 |
ExplorEnz | 1.4.3.23 |
PRIAM enzyme-specific profiles | 1.4.3.23 |
KEGG Ligand Database for Enzyme Nomenclature | 1.4.3.23 |
IUBMB Enzyme Nomenclature | 1.4.3.23 |
IntEnz | 1.4.3.23 |
MEDLINE | Find literature relating to 1.4.3.23 |
MetaCyc | 1.4.3.23 |
Rhea expert-curated reactions | 1.4.3.23 |
UniProtKB/Swiss-Prot |
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