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ENZYME entry: EC 1.4.3.26

Accepted Name
Pre-mycofactocin synthase.
Reaction catalysed
3-amino-5-((4-hydroxyphenyl)methyl)-4,4-dimethyl-2-pyrrolidin-2-one + O(2) + H(2)O <=> 5-((4-hydroxyphenyl)methyl)-4,4-dimethylpyrrolidine-2,3-dione + NH(3) + H(2)O(2)
Comment(s)
  • A flavoprotein (FMN).
  • The enzyme participates in the biosynthesis of the enzyme cofactor mycofactocin.
  • The enzyme uses oxygen as an electron source to oxidize a C-N bond, followed by spontaneous exchange with water to form an alpha-keto moiety on the resulting molecule.
Cross-references
BRENDA1.4.3.26
EC2PDB1.4.3.26
ExplorEnz1.4.3.26
PRIAM enzyme-specific profiles1.4.3.26
KEGG Ligand Database for Enzyme Nomenclature1.4.3.26
IUBMB Enzyme Nomenclature1.4.3.26
IntEnz1.4.3.26
MEDLINEFind literature relating to 1.4.3.26
MetaCyc1.4.3.26
Rhea expert-curated reactions1.4.3.26
UniProtKB/Swiss-Prot
A0QSB9, MFTD_MYCS2;  P9WND6, MFTD_MYCTO;  P9WND7, MFTD_MYCTU;  
A0PM50, MFTD_MYCUA;  

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