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ENZYME

ENZYME entry: EC 1.4.7.1

PURL: https://purl.expasy.org/enzyme/EC/1.4.7.1
Accepted Name
glutamate synthase (ferredoxin)
Alternative Name(s)
ferredoxin-dependent glutamate synthase
Reaction catalysed
2 oxidized [2Fe-2S]-[ferredoxin] + 2 L-glutamate = L-glutamine + 2 reduced [2Fe-2S]-[ferredoxin] + 2-oxoglutarate + 2 H(+)
Comment(s)
  • The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate.
  • The NH3 is channeled through a 24 A channel in the active protein.
  • No hydrolysis of glutamine takes place without ferredoxin and 2-oxoglutarate being bound to the protein.
Cross-references
BRENDA1.4.7.1
EC2PDB1.4.7.1
ExplorEnz1.4.7.1
KEGG Ligand Database for Enzyme Nomenclature1.4.7.1
IUBMB Enzyme Nomenclature1.4.7.1
MEDLINEFind literature relating to 1.4.7.1
MetaCyc1.4.7.1
Rhea expert-curated reactions1.4.7.1
UniProtKB/Swiss-Prot
Q9ZNZ7, GLTB1_ARATHQ9T0P4, GLTB2_ARATHQ06434, GLTB_ANTSP
O19906, GLTB_CYACAQ08258, GLTB_HORVUP23225, GLTB_MAIZE
Q69RJ0, GLTB_ORYSJP51375, GLTB_PORPUQ1XDB2, GLTB_PYRYE
Q43155, GLTB_SPIOLP55037, GLTB_SYNY3P55038, GLTS_SYNY3

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-