ID 1.5.1.1 DE 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase DE [NAD(P)H]. AN pyrroline-2-carboxylate reductase. CA (1) L-pipecolate + NADP(+) = Delta(1)-piperideine-2-carboxylate + H(+) + CA NADPH. CA (2) L-pipecolate + NAD(+) = Delta(1)-piperideine-2-carboxylate + H(+) + CA NADH. CA (3) L-proline + NADP(+) = 1-pyrroline-2-carboxylate + H(+) + NADPH. CA (4) L-proline + NAD(+) = 1-pyrroline-2-carboxylate + H(+) + NADH. CC -!- The enzymes, characterized from the bacterium Azospirillum CC brasilense, is involved in trans-3-hydroxy-L-proline metabolism. CC -!- In contrast to EC 1.5.1.21, which is specific for NADPH, this enzyme CC shows similar activity with NADPH and NADH. DR V5YW53, PY2CR_AZOBR; //