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ENZYME

ENZYME entry: EC 1.5.1.2

Accepted Name
pyrroline-5-carboxylate reductase
Alternative Name(s)
P5CR
Reaction catalysed
  • L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH
  • L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH
Comment(s)
Also reduces 1-pyrroline-3-hydroxy-5-carboxylate to L-hydroxyproline.
Cross-references
BRENDA1.5.1.2
EC2PDB1.5.1.2
ExplorEnz1.5.1.2
PRIAM enzyme-specific profiles1.5.1.2
KEGG Ligand Database for Enzyme Nomenclature1.5.1.2
IUBMB Enzyme Nomenclature1.5.1.2
IntEnz1.5.1.2
MEDLINEFind literature relating to 1.5.1.2
MetaCyc1.5.1.2
Rhea expert-curated reactions1.5.1.2
UniProtKB/Swiss-Prot
P54904, P5CR1_ARATHE0TY11, P5CR1_BACSHP0CI77, P5CR1_BACSU
Q58DT4, P5CR1_BOVINQ54IL7, P5CR1_DICDIP32322, P5CR1_HUMAN
Q922W5, P5CR1_MOUSEQ5R9X6, P5CR1_PONABP54552, P5CR2_BACSU
Q17QJ7, P5CR2_BOVINQ55E34, P5CR2_DICDIQ96C36, P5CR2_HUMAN
Q4R6W7, P5CR2_MACFAQ922Q4, P5CR2_MOUSEQ5RAQ3, P5CR2_PONAB
Q6AY23, P5CR2_RATQ00777, P5CR3_BACSUQ58D08, P5CR3_BOVIN
Q5SPD7, P5CR3_DANREQ53H96, P5CR3_HUMANQ4R531, P5CR3_MACFA
Q9DCC4, P5CR3_MOUSEQ5PQJ6, P5CR3_RATA1L2Q8, P5CR3_XENLA
O04016, P5CR_ACTCCO66553, P5CR_AQUAEQ20848, P5CR_CAEEL
P0C1E4, P5CR_CORGLP0C1E5, P5CR_CORMLP0A9L8, P5CR_ECOLI
P43869, P5CR_HAEINQ9ZK56, P5CR_HELPJO25773, P5CR_HELPY
Q6CR99, P5CR_KLULAQ12740, P5CR_LOPARQ9HH99, P5CR_METAC
P22350, P5CR_METSMP46725, P5CR_MYCLEP9WHU6, P5CR_MYCTO
P9WHU7, P5CR_MYCTUQ12641, P5CR_NEUCRQ9CPE8, P5CR_PASMU
Q04708, P5CR_PEAP22008, P5CR_PSEAEQ9P7Y7, P5CR_SCHPO
P0A9L9, P5CR_SHIFLP17817, P5CR_SOYBNQ5HFR9, P5CR_STAAC
Q99TZ0, P5CR_STAAMQ7A5G8, P5CR_STAANQ6GGJ5, P5CR_STAAR
Q6G961, P5CR_STAASQ7A0U1, P5CR_STAAWQ5HP48, P5CR_STAEQ
Q8CP51, P5CR_STAESQ4L6K3, P5CR_STAHJQ49XV0, P5CR_STAS1
P74572, P5CR_SYNY3P54893, P5CR_THET2P27771, P5CR_TREPA
P52053, P5CR_VIBALP32263, P5CR_YEASTL0E163, PHQD_PENFE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.1.-
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