Expasy logo

ENZYME

ENZYME entry: EC 1.5.1.27

Accepted Name
1,2-dehydroreticulinium reductase (NADPH)
Alternative Name(s)
1,2-dehydroreticulinium ion reductase
Reaction catalysed
(R)-reticuline + NADP(+) <=> 1,2-dehydroreticuline + H(+) + NADPH
Comment(s)
  • Reduces the 1,2-dehydroreticulinium ion to (R)-reticuline, which is a direct precursor of morphinan alkaloids in the poppy plant.
  • The enzyme does not catalyze the reverse reaction to any significant extent under physiological conditions.
Cross-references
BRENDA1.5.1.27
EC2PDB1.5.1.27
ExplorEnz1.5.1.27
PRIAM enzyme-specific profiles1.5.1.27
KEGG Ligand Database for Enzyme Nomenclature1.5.1.27
IUBMB Enzyme Nomenclature1.5.1.27
IntEnz1.5.1.27
MEDLINEFind literature relating to 1.5.1.27
MetaCyc1.5.1.27
Rhea expert-curated reactions1.5.1.27
UniProtKB/Swiss-Prot
P0DKI7, STORR_PAPSO

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-