A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.5.1.27
| Accepted Name |
|---|
| 1,2-dehydroreticulinium reductase (NADPH).
|
| Alternative Name(s) |
|---|
| 1,2-dehydroreticulinium ion reductase. |
| Reaction catalysed |
|---|
| (R)-reticuline + NADP(+) <=> 1,2-dehydroreticulinium + NADPH |
| Comment(s) |
|---|
- Reduces the 1,2-dehydroreticulinium ion to (R)-reticuline, which is a
direct precursor of morphinan alkaloids in the poppy plant.
- The enzyme does not catalyze the reverse reaction to any significant
extent under physiological conditions.
|
| Cross-references |
|---|
| BRENDA | 1.5.1.27 |
| EC2PDB | 1.5.1.27 |
| ExplorEnz | 1.5.1.27 |
| PRIAM enzyme-specific profiles | 1.5.1.27 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.5.1.27 |
| IUBMB Enzyme Nomenclature | 1.5.1.27 |
| IntEnz | 1.5.1.27 |
| MEDLINE | Find literature relating to 1.5.1.27 |
| MetaCyc | 1.5.1.27 |
| UniProtKB/Swiss-Prot |
|
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