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ENZYME entry: EC 1.5.1.31

Accepted Name
berberine reductase.
Alternative Name(s)
(R)-canadine synthase.
Reaction catalysed
(R)-canadine + 2 NADP(+) <=> berberine + H(+) + 2 NADPH
Comment(s)
  • Involved in alkaloid biosynthesis in Corydalis cava to give (R)- canadine with the opposite configuration to the precursor of berberine (see EC 1.3.3.8).
  • Also acts on 7,8-dihydroberberine.
Cross-references
BRENDA1.5.1.31
EC2PDB1.5.1.31
ExplorEnz1.5.1.31
PRIAM enzyme-specific profiles1.5.1.31
KEGG Ligand Database for Enzyme Nomenclature1.5.1.31
IUBMB Enzyme Nomenclature1.5.1.31
IntEnz1.5.1.31
MEDLINEFind literature relating to 1.5.1.31
MetaCyc1.5.1.31
Rhea expert-curated reactions1.5.1.31

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-