ID 1.5.1.43 DE carboxynorspermidine synthase. AN carboxynorspermidine dehydrogenase. AN carboxyspermidine dehydrogenase. CA (1) carboxynorspermidine + H2O + NADP(+) = H(+) + L-aspartate CA 4-semialdehyde + NADPH + propane-1,3-diamine. CA (2) carboxyspermidine + H2O + NADP(+) = H(+) + L-aspartate 4-semialdehyde CA + NADPH + putrescine. CC -!- The reaction takes place in the opposite direction. CC -!- Part of a bacterial polyamine biosynthesis pathway. CC -!- L-aspartate 4-semialdehyde and propane-1,3-diamine/putrescine form a CC Schiff base that is reduced to form CC carboxynorspermidine/carboxyspermidine, respectively. CC -!- The enzyme from the bacterium Vibrio cholerae is essential for CC biofilm formation. CC -!- The enzyme from Campylobacter jejuni only produces carboxyspermidine CC in vivo even though it also can produce carboxynorspermidine in CC vitro. DR P0DPE4, CANSD_VIBAX; Q9KRL3, CANSD_VIBCH; //