ID   1.5.1.46
DE   agroclavine dehydrogenase.
CA   agroclavine + NADP(+) = didehydroagroclavine + H(+) + NADPH.
CC   -!- The enzyme participates in the biosynthesis of ergotamine, an ergot
CC       alkaloid produced by some fungi of the Clavicipitaceae family.
CC   -!- The reaction is catalyzed in the opposite direction to that shown.
CC   -!- The substrate for the enzyme is an iminium intermediate that is
CC       formed spontaneously from chanoclavine-I aldehyde in the presence of
CC       glutathione.
DR   A8C7S1, EASG_CLAFS ;  M1WEN5, EASG_CLAP2 ;  P0CT21, EASG_CLAPU ;
DR   A2TBU1, EASG_EPIFI ;
//