ID 1.5.1.56 DE 3,17-didehydrostemmadenine reductase. CA 17-dehydrostemmadenine + NADP(+) = 3,17-didehydrostemmadenine + NADPH. CC -!- The enzyme, characterized from the plant Catharanthus roseus CC (Madagascar periwinkle), participates in a biosynthetic pathway that CC leads to production of the bisindole alkaloid compounds vinblastine CC and vincristine, which are used as anticancer drugs. CC -!- Both the substrate and the product of the enzyme are unstable. DR A0A2P1GIW4, REDX1_CATRO; //