ID   1.5.3.10
DE   dimethylglycine oxidase.
CA   N,N-dimethylglycine + (6S)-5,6,7,8-tetrahydrofolate + O2 = sarcosine +
CA   (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O2.
CC   -!- A flavoprotein (FAD).
CC   -!- The enzyme, characterized from the bacterium Arthrobacter
CC       globiformis, contains two active sites connected by a large 'reaction
CC       chamber'.
CC   -!- An imine intermediate is transferred between the sites, eliminating
CC       the production of toxic formaldehyde.
CC   -!- In the absence of folate the enzyme does form formaldehyde.
CC   -!- Does not oxidize sarcosine. cf. EC 1.5.8.4.
DR   Q9AGP8, DMGO_ARTGO ;
//