ID   1.5.3.17
DE   Non-specific polyamine oxidase.
AN   Polyamine oxidase.
CA   (1) Spermine + O(2) + H(2)O = spermidine + 3-aminopropanal + H(2)O(2).
CA   (2) Spermidine + O(2) + H(2)O = putrescine + 3-aminopropanal + H(2)O(2).
CA   (3) N(1)-acetylspermine + O(2) + H(2)O = spermidine + 3-acetamidopropanal
CA   + H(2)O(2).
CA   (4) N(1)-acetylspermidine + O(2) + H(2)O = putrescine +
CA   3-acetamidopropanal + H(2)O(2).
CF   FAD.
CC   -!- The non-specific polyamine oxidases may differ from each other
CC       considerably.
CC   -!- The enzyme from Saccharomyces cerevisiae shows a rather broad
CC       specificity and also oxidizes N(8)-acetylspermidine.
CC   -!- The enzyme from Ascaris suum shows high activity with spermine and
CC       spermidine, but also oxidizes norspermine.
CC   -!- The enzyme from Arabidopsis thaliana shows high activity with
CC       spermidine, but also oxidizes other polyamines.
CC   -!- The specific polyamine oxidases are classified as EC 1.5.3.13,
CC       EC 1.5.3.14, EC 1.5.3.15 and EC 1.5.3.16.
CC   -!- Formerly EC 1.5.3.11, EC 1.5.3.n1, EC 1.5.3.n2 and EC 1.5.3.n4.
DR   P50264, FMS1_YEAST ;  Q9FNA2, PAO1_ARATH ;  Q9LYT1, PAO3_ARATH ;
//