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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.5.3.23

Accepted Name
Glyphosate oxidoreductase.
Reaction catalysed
2 glyphosate + O(2) <=> 2 aminomethylphosphonate + 2 glyoxylate
Cofactor(s)
FAD.
Comment(s)
  • Characterized from the bacterium Ochrobactrum sp. G-1.
  • The catalytic cycle starts with a reduction of the FAD cofactor by one molecule of glyphosate, yielding reduced FAD and a Schiff base of aminomethylphosphonate with glyoxylate that is hydrolyzed to the single components.
  • The reduced FAD is reoxidized by oxygen, generating water and an oxygenated flavin intermediate, which catalyzes the oxygenation of a second molecule of glyphosate, forming the second pair of aminomethylphosphonate and glyoxylate.
Cross-references
BRENDA1.5.3.23
EC2PDB1.5.3.23
ExplorEnz1.5.3.23
PRIAM enzyme-specific profiles1.5.3.23
KEGG Ligand Database for Enzyme Nomenclature1.5.3.23
IUBMB Enzyme Nomenclature1.5.3.23
IntEnz1.5.3.23
MEDLINEFind literature relating to 1.5.3.23
MetaCyc1.5.3.23

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-