ID   1.5.3.25
DE   fructosyl amine oxidase (glucosone-forming).
AN   amadoriase.
CA   an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2 = 2-dehydro-D-
CA   glucose + an aliphatic amine + H2O2.
CC   -!- Reducing sugars such as glucose react with amino groups in proteins
CC       via the spontaeous Maillard reaction, forming an unstable product
CC       that undergoes spontaneous rearrangement to a keto amine compound.
CC   -!- These reactions are known as glycation reactions, and the stable
CC       products are known as Amadori products.
CC   -!- This enzyme, which contains an FAD cofactor, catalyzes a deglycation
CC       reaction that regenerates the amine reactant.
CC   -!- By-products are glucosone and hydrogen peroxide.
CC   -!- The enzymes have been reported from fungi and bacteria, but not from
CC       higher eukaryotes.
CC   -!- Specific enzymes differ in their substrate specificity. cf.
CC       EC 1.5.3.26.
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