A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.5.4.1
| Accepted Name |
|---|
| Pyrimidodiazepine synthase.
|
| Reaction catalysed |
|---|
| 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido(4,5-b)[1,4]diazepin-4-one + glutathione disulfide + H(2)O <=> 6-pyruvoyltetrahydropterin + 2 glutathione |
| Comment(s) |
|---|
- In the reverse direction of reaction, the reduction of 6-pyruvoyl-
tetrahydropterin is accompanied by the opening of the 6-membered
pyrazine ring and the formation of the 7-membered diazepine ring.
- The pyrimidodiazepine involved is an acetyldihydro derivative.
- Involved in the formation of the eye pigment drosopterin in
Drosophila melanogaster.
|
| Cross-references |
|---|
| BRENDA | 1.5.4.1 |
| EC2PDB | 1.5.4.1 |
| ExplorEnz | 1.5.4.1 |
| PRIAM enzyme-specific profiles | 1.5.4.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.5.4.1 |
| IUBMB Enzyme Nomenclature | 1.5.4.1 |
| IntEnz | 1.5.4.1 |
| MEDLINE | Find literature relating to 1.5.4.1 |
| MetaCyc | 1.5.4.1 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.5.4.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.5.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-