ENZYME entry: EC 1.5.98.1

PURL: https://purl.expasy.org/enzyme/EC/1.5.98.1

Accepted Name

methylenetetrahydromethanopterin dehydrogenase

Alternative Name(s)

5,10-methylenetetrahydromethanopterin dehydrogenase

N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase

Reaction catalysed

5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)

Comment(s)

Coenzyme F420 is a 7,8-didemethyl-8-hydroxy-5-deazariboflavin derivative; methanopterin is a pterin analog.
The enzyme is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum.
Formerly EC 1.5.99.9.

Cross-references

BRENDA

1.5.98.1

EC2PDB

1.5.98.1

ExplorEnz

1.5.98.1

KEGG Ligand Database for Enzyme Nomenclature

1.5.98.1

IUBMB Enzyme Nomenclature

1.5.98.1

MEDLINE

Find literature relating to 1.5.98.1

MetaCyc

1.5.98.1

Rhea expert-curated reactions

1.5.98.1

UniProtKB/Swiss-Prot

O29544, MTD_ARCFU	A6UWS1, MTD_META3	Q8THT2, MTD_METAC
A7I5N7, MTD_METB6	Q2FU89, MTD_METHJ	Q58441, MTD_METJA
P94951, MTD_METKA	A2SPK1, MTD_METLZ	A4FZG7, MTD_METM5
A6VJ05, MTD_METM7	Q8PXV8, MTD_METMA	A3CSZ5, MTD_METMJ
Q6M099, MTD_METMP	B8GJQ7, MTD_METPE	A5UMI1, MTD_METS3
Q2NHQ2, MTD_METST	Q50501, MTD_METTH	P55300, MTD_METTM
A6URY5, MTD_METVS

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.98.-
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