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ENZYME

ENZYME entry: EC 1.5.98.2

Accepted Name
5,10-methylenetetrahydromethanopterin reductase
Alternative Name(s)
5,10-methylenetetrahydromethanopterin cyclohydrolase
coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase
methylene-H4MPT reductase
N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase
N(5),N(10)-methylenetetrahydromethanopterin reductase
Reaction catalysed
5-methyl-5,6,7,8-tetrahydromethanopterin + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)
Comment(s)
  • Catalyzes an intermediate step in methanogenesis from CO2 and H2 in archaea.
  • Formerly EC 1.5.99.11.
Cross-references
BRENDA1.5.98.2
EC2PDB1.5.98.2
ExplorEnz1.5.98.2
PRIAM enzyme-specific profiles1.5.98.2
KEGG Ligand Database for Enzyme Nomenclature1.5.98.2
IUBMB Enzyme Nomenclature1.5.98.2
IntEnz1.5.98.2
MEDLINEFind literature relating to 1.5.98.2
MetaCyc1.5.98.2
Rhea expert-curated reactions1.5.98.2
UniProtKB/Swiss-Prot
O29196, MER_ARCFUQ8TJP7, MER_METACQ46FV4, MER_METBF
Q58929, MER_METJAQ8TXY4, MER_METKAQ8PZ66, MER_METMA
O27784, MER_METTHQ9UXP0, MER_METTIQ50744, MER_METTM

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