A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.5.99.12
| Accepted Name |
|---|
| Cytokinin dehydrogenase.
|
| Alternative Name(s) |
|---|
| Cytokinin oxidase. |
| Reaction catalysed |
|---|
| N(6)-dimethylallyladenine + acceptor + H(2)O <=> adenine + 3-methylbut-2-enal + reduced acceptor |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- Converts zeatin and related cytokinins.
- Catalyzes the oxidation of cytokinins, a family of N(6)-substituted
adenine derivatives that are plant hormones, where the substituent is
a dimethylallyl or other prenyl group.
- Although this activity was previously thought to be catalyzed by a
hydrogen-peroxide-forming oxidase, this enzyme does not require
oxygen for activity and does not form hydrogen peroxide.
- 2,6-dichloroindophenol, methylene blue, nitroblue tetrazolium,
phenazine methosulfate and Cu(2+) in the presence of imidazole can
act as acceptors.
|
| Cross-references |
|---|
| BRENDA | 1.5.99.12 |
| EC2PDB | 1.5.99.12 |
| ExplorEnz | 1.5.99.12 |
| PRIAM enzyme-specific profiles | 1.5.99.12 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.5.99.12 |
| IUBMB Enzyme Nomenclature | 1.5.99.12 |
| IntEnz | 1.5.99.12 |
| MEDLINE | Find literature relating to 1.5.99.12 |
| MetaCyc | 1.5.99.12 |
| UniProtKB/Swiss-Prot |
| Q5Z620, CKX10_ORYSJ; | Q6Z955, CKX11_ORYSJ; | O22213, CKX1_ARATH; |
| Q9T0N8, CKX1_MAIZE; | Q0JQ12, CKX1_ORYSJ; | Q9FUJ3, CKX2_ARATH; |
| Q4ADV8, CKX2_ORYSJ; | Q9LTS3, CKX3_ARATH; | Q8LNV6, CKX3_ORYSJ; |
| Q9FUJ2, CKX4_ARATH; | Q5JLP4, CKX4_ORYSJ; | Q67YU0, CKX5_ARATH; |
| Q5ZAY9, CKX5_ORYSJ; | Q9LY71, CKX6_ARATH; | Q6YW51, CKX6_ORYSJ; |
| Q9FUJ1, CKX7_ARATH; | Q6YW50, CKX7_ORYSJ; | A2XVN3, CKX8_ORYSI; |
| A3AVP1, CKX8_ORYSJ; | Q75K78, CKX9_ORYSJ; | P58763, CKX_WHEAT; |
|
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