ENZYME entry: EC 1.5.99.12
Accepted Name |
Cytokinin dehydrogenase.
|
Alternative Name(s) |
Cytokinin oxidase. |
Reaction catalysed |
N(6)-prenyladenine + acceptor + H(2)O <=> adenine + 3-methylbut-2-enal + reduced acceptor |
Cofactor(s) |
FAD.
|
Comment(s) |
- Catalyzes the oxidation of cytokinins, a family of N(6)-substituted
adenine derivatives that are plant hormones, where the substituent is
a prenyl group.
- Although this activity was previously thought to be catalyzed by a
hydrogen-peroxide-forming oxidase, this enzyme does not require
oxygen for activity and does not form hydrogen peroxide.
- 2,6-dichloroindophenol, methylene blue, nitroblue tetrazolium,
phenazine methosulfate and copper(II) in the presence of imidazole
can act as acceptors.
- This enzyme plays a part in regulating rice-grain production, with
lower levels of the enzyme resulting in enhanced grain production.
|
Cross-references |
BRENDA | 1.5.99.12 |
EC2PDB | 1.5.99.12 |
ExplorEnz | 1.5.99.12 |
PRIAM enzyme-specific profiles | 1.5.99.12 |
KEGG Ligand Database for Enzyme Nomenclature | 1.5.99.12 |
IUBMB Enzyme Nomenclature | 1.5.99.12 |
IntEnz | 1.5.99.12 |
MEDLINE | Find literature relating to 1.5.99.12 |
MetaCyc | 1.5.99.12 |
Rhea expert-curated reactions | 1.5.99.12 |
UniProtKB/Swiss-Prot |
Q5Z620, CKX10_ORYSJ; | Q6Z955, CKX11_ORYSJ; | O22213, CKX1_ARATH; |
Q9T0N8, CKX1_MAIZE; | Q0JQ12, CKX1_ORYSJ; | Q9FUJ3, CKX2_ARATH; |
Q4ADV8, CKX2_ORYSJ; | Q9LTS3, CKX3_ARATH; | Q8LNV6, CKX3_ORYSJ; |
Q9FUJ2, CKX4_ARATH; | Q5JLP4, CKX4_ORYSJ; | Q67YU0, CKX5_ARATH; |
Q5ZAY9, CKX5_ORYSJ; | Q9LY71, CKX6_ARATH; | Q6YW51, CKX6_ORYSJ; |
Q9FUJ1, CKX7_ARATH; | Q6YW50, CKX7_ORYSJ; | A2XVN3, CKX8_ORYSI; |
A3AVP1, CKX8_ORYSJ; | Q75K78, CKX9_ORYSJ; | P58763, CKX_WHEAT; |
|
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UniProtKB/Swiss-Prot entries corresponding to 1.5.99.-
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