ID 1.5.99.15 DE dihydromethanopterin reductase (acceptor). CA 5,6,7,8-tetrahydromethanopterin + A = 7,8-dihydromethanopterin + AH2. CC -!- This archaeal enzyme catalyzes the last step in the biosynthesis of CC tetrahydromethanopterin, a cofactor used in methanogenesis. CC -!- The enzyme is characterized from the archaea Methanosarcina mazei and CC Methanocaldococcus jannaschii. cf. EC 1.5.1.47. DR Q57661, DMRX_METJA ; Q8PVV3, DMRX_METMA ; //