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ENZYME entry: EC 1.5.99.4

Accepted Name
Nicotine dehydrogenase.
Alternative Name(s)
L-nicotine oxidase.
Reaction catalysed
(S)-nicotine + acceptor + H(2)O <=> (S)-6-hydroxynicotine + reduced acceptor
Cofactor(s)
FMN.
Comment(s)
The enzyme can act on both the naturally found (S)-enantiomer and the synthetic (R)-enantiomer of nicotine, with retention of configuration in both cases.
Cross-references
BRENDA1.5.99.4
EC2PDB1.5.99.4
ExplorEnz1.5.99.4
PRIAM enzyme-specific profiles1.5.99.4
KEGG Ligand Database for Enzyme Nomenclature1.5.99.4
IUBMB Enzyme Nomenclature1.5.99.4
IntEnz1.5.99.4
MEDLINEFind literature relating to 1.5.99.4
MetaCyc1.5.99.4
Rhea expert-curated reactions1.5.99.4

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