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ENZYME

ENZYME entry: EC 1.6.3.2

Accepted Name
NAD(P)H oxidase (H2O-forming)
Reaction catalysed
  • 2 H(+) + 2 NADPH + O2 = 2 H2O + 2 NADP(+)
  • 2 H(+) + 2 NADH + O2 = 2 H2O + 2 NAD(+)
Comment(s)
  • NADPH is a better substrate than NADH.
  • By removal of oxygen the enzyme is involved in aerobic tolerance in the thermophilic anaerobic archaeon Thermococcus profundus and in Giardia intestinalis, a microaerophilic single-celled parasite of the order Diplomonadida.
Cross-references
BRENDA1.6.3.2
EC2PDB1.6.3.2
ExplorEnz1.6.3.2
PRIAM enzyme-specific profiles1.6.3.2
KEGG Ligand Database for Enzyme Nomenclature1.6.3.2
IUBMB Enzyme Nomenclature1.6.3.2
IntEnz1.6.3.2
MEDLINEFind literature relating to 1.6.3.2
MetaCyc1.6.3.2
Rhea expert-curated reactions1.6.3.2
UniProtKB/Swiss-Prot
Q5JGP4, NSR_THEKO

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