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ENZYME entry: EC 1.6.5.10

Accepted Name
NADPH dehydrogenase (quinone).
Reaction catalysed
NADPH + a quinone <=> NADP(+) + a quinol
Cofactor(s)
Flavoprotein.
Comment(s)
  • The enzyme from Escherichia coli is specific for NADPH and is most active with quinone derivatives and ferricyanide as electron acceptors.
  • Menaquinone can act as acceptor.
  • The enzyme from hog liver is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol.
  • Formerly EC 1.6.99.6.
Cross-references
BRENDA1.6.5.10
EC2PDB1.6.5.10
ExplorEnz1.6.5.10
PRIAM enzyme-specific profiles1.6.5.10
KEGG Ligand Database for Enzyme Nomenclature1.6.5.10
IUBMB Enzyme Nomenclature1.6.5.10
IntEnz1.6.5.10
MEDLINEFind literature relating to 1.6.5.10
MetaCyc1.6.5.10
UniProtKB/Swiss-Prot
P0AEY7, MDAB_ECO57;  P0AEY6, MDAB_ECOL6;  P0AEY5, MDAB_ECOLI;  
P44803, MDAB_HAEIN;  

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