ENZYME entry: EC 1.6.5.9
| Accepted Name |
|---|
| NADH:ubiquinone reductase (non-electrogenic).
|
| Alternative Name(s) |
|---|
| Coenzyme Q reductase. |
| Electron transfer complex I. |
| NADH(2) dehydrogenase (ubiquinone). |
| NADH-coenzyme Q oxidoreductase. |
| NADH-coenzyme Q reductase. |
| NADH-CoQ oxidoreductase. |
| NADH-CoQ reductase. |
| NADH-Q6 oxidoreductase. |
| NADH-ubiquinone oxidoreductase. |
| NADH-ubiquinone reductase. |
| Ubiquinone reductase. |
| Reaction catalysed |
|---|
| NADH + a quinone <=> NAD(+) + a quinol |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- A flavoprotein (FAD or FMN).
- Occurs in mitochondria of yeast and plants, and in aerobic bacteria.
- Has low activity with NADPH.
- Unlike EC 7.1.1.2, this enzyme does not pump proteons of sodium ions
across the membrane.
- It is also not sensitive to rotenone.
|
| Cross-references |
|---|
| BRENDA | 1.6.5.9 |
| EC2PDB | 1.6.5.9 |
| ExplorEnz | 1.6.5.9 |
| PRIAM enzyme-specific profiles | 1.6.5.9 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.6.5.9 |
| IUBMB Enzyme Nomenclature | 1.6.5.9 |
| IntEnz | 1.6.5.9 |
| MEDLINE | Find literature relating to 1.6.5.9 |
| MetaCyc | 1.6.5.9 |
| UniProtKB/Swiss-Prot |
| M1BYJ7, ENDB1_SOLTU; | M0ZYF3, INDA1_SOLTU; | Q8GWA1, NDA1_ARATH; |
| Q9ST63, NDA1_SOLTU; | O80874, NDA2_ARATH; | Q1JPL4, NDB1_ARATH; |
| Q9ST62, NDB1_SOLTU; | Q94BV7, NDB2_ARATH; | F4JJJ3, NDB3_ARATH; |
| Q9SKT7, NDB4_ARATH; | Q8GXR9, NDC1_ARATH; | O14121, NDH1_SCHPO; |
| P40215, NDH1_YEAST; | O43090, NDH2_SCHPO; | F2Z699, NDH2_YARLI; |
| Q07500, NDH2_YEAST; | P39755, NDHF_BACSU; | P32340, NDI1_YEAST; |
| Q9I4V0, NQRED_PSEAE; |
|
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UniProtKB/Swiss-Prot entries corresponding to 1.6.5.-
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