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ENZYME entry: EC 1.6.99.3

Accepted Name
NADH dehydrogenase.
Alternative Name(s)
Beta-NADH dehydrogenase dinucleotide.
Cytochrome c reductase.
Diaphorase.
Dihydrocodehydrogenase I dehydrogenase.
Dihydronicotinamide adenine dinucleotide dehydrogenase.
Diphosphopyrinase.
DPNH diaphorase.
NADH diaphorase.
NADH hydrogenase.
NADH oxidoreductase.
NADH-menadione oxidoreductase.
NADH:cytochrome c oxidoreductase.
Reduced diphosphopyridine nucleotide diaphorase.
Type 1 dehydrogenase.
Type I dehydrogenase.
Reaction catalysed
NADH + acceptor <=> NAD(+) + reduced acceptor
Cofactor(s)
Flavoprotein; Iron-sulfur.
Comment(s)
  • After preparations have been subjected to certain treatments cytochrome c may act as acceptor.
  • Under normal conditions, two protons are extruded from the cytoplasm or the intramitochondrial or stromal compartment.
  • Present in a mitochondrial complex as EC 7.1.1.2.
  • Formerly EC 1.6.2.1.
Cross-references
PROSITEPDOC00496
BRENDA1.6.99.3
EC2PDB1.6.99.3
ExplorEnz1.6.99.3
PRIAM enzyme-specific profiles1.6.99.3
KEGG Ligand Database for Enzyme Nomenclature1.6.99.3
IUBMB Enzyme Nomenclature1.6.99.3
IntEnz1.6.99.3
MEDLINEFind literature relating to 1.6.99.3
MetaCyc1.6.99.3

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