Home  |  Contact
Due to maintenance work, this service will be unavailable Mon Feb 13 between 07:00 and 09:30 - CET. Apologies for the inconvenience.

ENZYME entry: EC

Accepted Name
nitrite reductase (NO-forming).
Alternative Name(s)
cd-cytochrome nitrite reductase.
cytochrome c-551:O2, NO2(+) oxidoreductase.
cytochrome cd.
cytochrome cd1.
hydroxylamine (acceptor) reductase.
methyl viologen-nitrite reductase.
nitrite reductase.
nitrite reductase (cytochrome; NO-forming).
nitrite reductase (cytochrome).
Pseudomonas cytochrome oxidase.
Reaction catalysed
Fe(III)-[cytochrome c] + H2O + nitric oxide <=> Fe(II)-[cytochrome c] + 2 H(+) + nitrite
  • The reaction is catalyzed by two types of enzymes, found in the perimplasm of denitrifying bacteria.
  • One type comprises proteins containing multiple copper centers, the other a heme protein, cytochrome cd1.
  • Acceptors include c-type cytochromes such as cytochrome c-550 or cytochrome c-551 from Paracoccus denitrificans or Pseudomonas aeruginosa, and small blue copper proteins such as azurin and pseudoazurin.
  • Cytochrome cd1 also has oxidase and hydroxylamine reductase activities.
  • May also catalyze the reaction of EC since this is a well- known activity of cytochrome cd1.
  • Formerly EC, EC and EC
PRIAM enzyme-specific profiles1.7.2.1
KEGG Ligand Database for Enzyme Nomenclature1.7.2.1
IUBMB Enzyme Nomenclature1.7.2.1
MEDLINEFind literature relating to
Rhea expert-curated reactions1.7.2.1
Q92Z29, NIRK_RHIME;  Q51700, NIRS_PARDP;  P72181, NIRS_PARPN;  
P24474, NIRS_PSEAE;  P24040, NIRS_STUST;  P25006, NIR_ACHCY;  
P38501, NIR_ALCFA;  P81445, NIR_ALCXX;  Q53239, NIR_CERS5;  
Q01537, NIR_NEOGA;  Q06006, NIR_PSECL;  Q60214, NIR_RHISU;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.7.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-