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ENZYME

ENZYME entry: EC 1.7.2.1

PURL: https://purl.expasy.org/enzyme/EC/1.7.2.1
Accepted Name
nitrite reductase (NO-forming)
Alternative Name(s)
cd-cytochrome nitrite reductase
cytochrome c-551:O2, NO2(+) oxidoreductase
cytochrome cd
cytochrome cd1
hydroxylamine (acceptor) reductase
methyl viologen-nitrite reductase
nitrite reductase
nitrite reductase (cytochrome; NO-forming)
nitrite reductase (cytochrome)
Pseudomonas cytochrome oxidase
Reaction catalysed
nitric oxide + Fe(III)-[cytochrome c] + H2O = Fe(II)-[cytochrome c] + nitrite + 2 H(+)
Comment(s)
  • The reaction is catalyzed by two types of enzymes, found in the perimplasm of denitrifying bacteria.
  • One type comprises proteins containing multiple copper centers, the other a heme protein, cytochrome cd1.
  • Acceptors include c-type cytochromes such as cytochrome c-550 or cytochrome c-551 from Paracoccus denitrificans or Pseudomonas aeruginosa, and small blue copper proteins such as azurin and pseudoazurin.
  • Cytochrome cd1 also has oxidase and hydroxylamine reductase activities.
  • May also catalyze the reaction of EC 1.7.99.1 since this is a well- known activity of cytochrome cd1.
  • Formerly EC 1.6.6.5, EC 1.7.99.3 and EC 1.9.3.2.
Cross-references
BRENDA1.7.2.1
EC2PDB1.7.2.1
ExplorEnz1.7.2.1
KEGG Ligand Database for Enzyme Nomenclature1.7.2.1
IUBMB Enzyme Nomenclature1.7.2.1
MEDLINEFind literature relating to 1.7.2.1
MetaCyc1.7.2.1
Rhea expert-curated reactions1.7.2.1
UniProtKB/Swiss-Prot
Q02219, ANIA_NEIGOQ9JTB8, ANIA_NEIMAQ9JYE1, ANIA_NEIMB
Q92Z29, NIRK_RHIMEQ51700, NIRS_PARDPP72181, NIRS_PARPN
P24474, NIRS_PSEAEP24040, NIRS_STUSTP25006, NIR_ACHCY
P38501, NIR_ALCFAP81445, NIR_ALCXXQ53239, NIR_CERS5
Q01537, NIR_NEOGAQ06006, NIR_PSECLQ60214, NIR_RHISU
P0DV45, NRHAO_KUEST

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