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ENZYME entry: EC

Accepted Name
hydroxylamine dehydrogenase.
Alternative Name(s)
hydroxylamine oxidase.
hydroxylamine oxidoreductase.
Reaction catalysed
4 Fe(III)-[cytochrome c] + H2O + hydroxylamine <=> 4 Fe(II)-[cytochrome c] + 5 H(+) + nitrite
  • The enzymes from the nitrifying bacterium Nitrosomonas europaea and the methylotrophic bacterium Methylococcus capsulatus are hemoproteins with seven c-type hemes and one specialized P460-type heme per subunit.
  • The enzyme converts hydroxylamine to nitrite via an enzyme-bound nitroxyl intermediate.
  • While nitrite is the main product, the enzyme from Nitrosomonas europaea can also produce nitric oxide by catalyzing the activity of EC
  • Formerly EC
PRIAM enzyme-specific profiles1.7.2.6
KEGG Ligand Database for Enzyme Nomenclature1.7.2.6
IUBMB Enzyme Nomenclature1.7.2.6
MEDLINEFind literature relating to
Rhea expert-curated reactions1.7.2.6

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