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ENZYME

ENZYME entry: EC 1.8.1.18

Accepted Name
NAD(P)H sulfur oxidoreductase (CoA-dependent)
Alternative Name(s)
coenzyme A-dependent NADPH sulfur oxidoreductase
S(0) reductase
Reaction catalysed
  • hydrogen sulfide + NADP(+) = NADPH + sulfur
  • hydrogen sulfide + NAD(+) = NADH + sulfur
Comment(s)
  • This enzyme, characterized from the archaeon Pyrococcus furiosus, is responsible for NAD(P)H-linked sulfur reduction.
  • The activity with NADH is about half of that with NADPH.
  • The reaction is dependent on CoA, although the nature of this dependency is not well understood.
Cross-references
BRENDA1.8.1.18
EC2PDB1.8.1.18
ExplorEnz1.8.1.18
PRIAM enzyme-specific profiles1.8.1.18
KEGG Ligand Database for Enzyme Nomenclature1.8.1.18
IUBMB Enzyme Nomenclature1.8.1.18
IntEnz1.8.1.18
MEDLINEFind literature relating to 1.8.1.18
MetaCyc1.8.1.18
Rhea expert-curated reactions1.8.1.18
UniProtKB/Swiss-Prot
Q9UYU5, NSR_PYRABQ8U1M0, NSR_PYRFUQ5JGP4, NSR_THEKO

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