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ENZYME entry: EC 1.8.1.18

Accepted Name
NAD(P)H sulfur oxidoreductase (CoA-dependent).
Alternative Name(s)
Coenzyme A-dependent NADPH sulfur oxidoreductase.
S(0) reductase.
Reaction catalysed
Hydrogen sulfide + NAD(P)(+) <=> sulfur + NAD(P)H
Cofactor(s)
FAD.
Comment(s)
  • This enzyme, characterized from the archaeon Pyrococcus furiosus, is responsible for NAD(P)H-linked sulfur reduction.
  • The activity with NADH is about half of that with NADPH.
  • The reaction is dependent on CoA, although the nature of this dependency is not well understood.
Cross-references
BRENDA1.8.1.18
EC2PDB1.8.1.18
ExplorEnz1.8.1.18
PRIAM enzyme-specific profiles1.8.1.18
KEGG Ligand Database for Enzyme Nomenclature1.8.1.18
IUBMB Enzyme Nomenclature1.8.1.18
IntEnz1.8.1.18
MEDLINEFind literature relating to 1.8.1.18
MetaCyc1.8.1.18
Rhea expert-curated reactions1.8.1.18
UniProtKB/Swiss-Prot
Q9UYU5, NSR_PYRAB;  Q8U1M0, NSR_PYRFU;  Q5JGP4, NSR_THEKO;  

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