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ENZYME

ENZYME entry: EC 1.8.1.7

Accepted Name
glutathione-disulfide reductase
Alternative Name(s)
glutathione reductase
glutathione reductase (NADPH)
glutathione S-reductase
GSH reductase
GSSG reductase
NADPH:oxidized-glutathione oxidoreductase
NADPH-glutathione reductase
NADPH-GSSG reductase
Reaction catalysed
2 glutathione + NADP(+) <=> glutathione disulfide + H(+) + NADPH
Comment(s)
  • Activity is dependent on a redox-active disulfide in each of the active centers.
  • Formerly EC 1.6.4.2.
Cross-references
BRENDA1.8.1.7
EC2PDB1.8.1.7
ExplorEnz1.8.1.7
PRIAM enzyme-specific profiles1.8.1.7
KEGG Ligand Database for Enzyme Nomenclature1.8.1.7
IUBMB Enzyme Nomenclature1.8.1.7
IntEnz1.8.1.7
MEDLINEFind literature relating to 1.8.1.7
MetaCyc1.8.1.7
Rhea expert-curated reactions1.8.1.7
UniProtKB/Swiss-Prot
P48641, GSHRC_ARATHO04955, GSHRC_BRARPP48642, GSHRC_ORYSJ
Q43621, GSHRC_PEAP42770, GSHRP_ARATHP27456, GSHRP_PEA
P48640, GSHRP_SOYBNQ43154, GSHRP_SPIOLP80461, GSHRP_TOBAC
P48639, GSHR_BURCEQ93379, GSHR_CAEELA2TIL1, GSHR_CALJA
Q6FRV2, GSHR_CANGAQ6BPI1, GSHR_DEBHAQ8T137, GSHR_DICDI
P06715, GSHR_ECOLIQ74ZK4, GSHR_EREGSP43783, GSHR_HAEIN
P00390, GSHR_HUMANQ6HA23, GSHR_KLULAP47791, GSHR_MOUSE
Q873E8, GSHR_NEUCRP48638, GSHR_NOSS1O15770, GSHR_PLAF7
Q94655, GSHR_PLAFKP23189, GSHR_PSEAEP70619, GSHR_RAT
P78965, GSHR_SCHPOP11804, GSHR_SPISPQ60151, GSHR_STRTR
Q6C5H4, GSHR_YARLIP41921, GSHR_YEASTP30635, TRXR2_CAEEL

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
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