Expasy logo

ENZYME

ENZYME entry: EC 1.8.2.2

Accepted Name
thiosulfate dehydrogenase
Alternative Name(s)
tetrathionate synthase
Reaction catalysed
2 Fe(III)-[cytochrome c] + 2 thiosulfate <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + tetrathionate
Comment(s)
  • The enzyme catalyzes the reversible formation of a sulfur-sulfur bond between the sulfane atoms of two thiosulfate molecules, yielding tetrathionate and releasing two electrons.
  • In many bacterial species the enzyme is a diheme c-type cytochrome.
  • In a number of organisms, including Thiomonas intermedia and Sideroxydans lithotrophicus, a second diheme cytochrome (TsdB) acts as the electron acceptor.
  • However, some organisms, such as Allochromatium vinosum, lack TsdB.
  • The electron acceptor in these organisms may be the high-potential iron-sulfur protein (HiPIP).
Cross-references
BRENDA1.8.2.2
EC2PDB1.8.2.2
ExplorEnz1.8.2.2
PRIAM enzyme-specific profiles1.8.2.2
KEGG Ligand Database for Enzyme Nomenclature1.8.2.2
IUBMB Enzyme Nomenclature1.8.2.2
IntEnz1.8.2.2
MEDLINEFind literature relating to 1.8.2.2
MetaCyc1.8.2.2
Rhea expert-curated reactions1.8.2.2
UniProtKB/Swiss-Prot
D3RVD4, TSDA_ALLVDQ4FQB7, TSDA_PSYA2A4VND8, TSDA_STUS1
D5WYQ5, TSDA_THIK1

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-