ENZYME entry: EC 1.8.3.5
Accepted Name |
Prenylcysteine oxidase.
|
Alternative Name(s) |
Prenylcysteine lyase. |
Reaction catalysed |
An S-prenyl-L-cysteine + O(2) + H(2)O <=> a prenal + L-cysteine + H(2)O(2) |
Cofactor(s) |
FAD.
|
Comment(s) |
- Cleaves the thioether bond of S-prenyl-L-cysteines, such as
S-farnesylcysteine and S-geranylgeranylcysteine.
- N-acetyl-prenylcysteine and prenylcysteinyl peptides are not
substrates.
- May represent the final step in the degradation of prenylated
proteins in mammalian tissues.
|
Cross-references |
BRENDA | 1.8.3.5 |
EC2PDB | 1.8.3.5 |
ExplorEnz | 1.8.3.5 |
PRIAM enzyme-specific profiles | 1.8.3.5 |
KEGG Ligand Database for Enzyme Nomenclature | 1.8.3.5 |
IUBMB Enzyme Nomenclature | 1.8.3.5 |
IntEnz | 1.8.3.5 |
MEDLINE | Find literature relating to 1.8.3.5 |
MetaCyc | 1.8.3.5 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.8.3.-
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