ID 1.8.4.16 DE thioredoxin:protein disulfide reductase. CA [protein]-dithiol + [thioredoxin]-disulfide = [protein]-disulfide + CA [thioredoxin]-dithiol. CC -!- The DsbD protein is found in Gram-negative bacteria and transfers CC electrons from cytoplasmic thioredoxin to the periplasmic substrate CC proteins DsbC, DsbG and CcmG, reducing disulfide bonds in the target CC proteins to dithiols. CC -!- NrdH redoxins, which are found in Gram-positive bacteria, catalyze a CC similar reaction. //