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ENZYME entry: EC 1.8.4.8

Accepted Name
Phosphoadenylyl-sulfate reductase (thioredoxin).
Alternative Name(s)
3'-phosphoadenylylsulfate reductase.
PAdoPS reductase.
PAPS reductase.
PAPS reductase, thioredoxin-dependent.
PAPS sulfotransferase.
Phosphoadenosine-phosphosulfate reductase.
Thioredoxin:3'-phospho-adenylylsulfate reductase.
Thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase.
Reaction catalysed
Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide <=> 3'-phosphoadenylyl sulfate + thioredoxin
Comment(s)
  • Specific for PAPS.
  • The enzyme from Escherichia coli will use thioredoxins from other species.
  • Formerly EC 1.8.99.4.
Cross-references
BRENDA1.8.4.8
EC2PDB1.8.4.8
ExplorEnz1.8.4.8
PRIAM enzyme-specific profiles1.8.4.8
KEGG Ligand Database for Enzyme Nomenclature1.8.4.8
IUBMB Enzyme Nomenclature1.8.4.8
IntEnz1.8.4.8
MEDLINEFind literature relating to 1.8.4.8
MetaCyc1.8.4.8
Rhea expert-curated reactions1.8.4.8
UniProtKB/Swiss-Prot
Q5E839, CYSH_ALIF1;  B5FGJ0, CYSH_ALIFM;  B6ELM6, CYSH_ALISL;  
Q0A6T1, CYSH_ALKEH;  B4RYS5, CYSH_ALTMD;  Q1LTP3, CYSH_BAUCH;  
B8D9K4, CYSH_BUCA5;  P57501, CYSH_BUCAI;  B8D7V6, CYSH_BUCAT;  
A8ANW8, CYSH_CITK8;  A7MJ65, CYSH_CROS8;  A7ZQK5, CYSH_ECO24;  
B7UHH4, CYSH_ECO27;  B7MKM9, CYSH_ECO45;  B7LEI1, CYSH_ECO55;  
Q8X7U3, CYSH_ECO57;  B5Z3C5, CYSH_ECO5E;  B7NT99, CYSH_ECO7I;  
B7MYR0, CYSH_ECO81;  B7LXH5, CYSH_ECO8A;  C4ZZR6, CYSH_ECOBW;  
B1XDH5, CYSH_ECODH;  A8A3P3, CYSH_ECOHS;  A1AEU8, CYSH_ECOK1;  
Q0TEA4, CYSH_ECOL5;  Q8FEI9, CYSH_ECOL6;  B1IUR7, CYSH_ECOLC;  
P17854, CYSH_ECOLI;  B7N6Z6, CYSH_ECOLU;  B6I6F6, CYSH_ECOSE;  
B1LQ85, CYSH_ECOSM;  Q1R7T6, CYSH_ECOUT;  A4WDV9, CYSH_ENT38;  
B2VG05, CYSH_ERWT9;  B7LWP0, CYSH_ESCF3;  Q7NK24, CYSH_GLOVI;  
B5XV26, CYSH_KLEP3;  A6TD47, CYSH_KLEP7;  Q6D1A3, CYSH_PECAS;  
C6DDH2, CYSH_PECCP;  Q7MB85, CYSH_PHOLL;  Q6LM60, CYSH_PHOPR;  
B4F233, CYSH_PROMH;  B5F429, CYSH_SALA4;  A9MF18, CYSH_SALAR;  
Q57KH9, CYSH_SALCH;  B5FTU1, CYSH_SALDC;  B5QW34, CYSH_SALEP;  
B5RDR9, CYSH_SALG2;  B4TFY3, CYSH_SALHS;  B4T473, CYSH_SALNS;  
Q5PEH9, CYSH_SALPA;  A9N2E4, CYSH_SALPB;  B5BEZ7, CYSH_SALPK;  
B4TTX7, CYSH_SALSV;  Q8Z460, CYSH_SALTI;  P17853, CYSH_SALTY;  
A8G9X8, CYSH_SERP5;  Q8EB01, CYSH_SHEON;  B2TZH2, CYSH_SHIB3;  
Q31XM6, CYSH_SHIBS;  Q32CG5, CYSH_SHIDS;  Q0T1I6, CYSH_SHIF8;  
Q7UBT0, CYSH_SHIFL;  Q3YY96, CYSH_SHISS;  Q2NVN2, CYSH_SODGM;  
Q55309, CYSH_SYNE7;  B1XN08, CYSH_SYNP2;  Q5N1N0, CYSH_SYNP6;  
P72794, CYSH_SYNY3;  P52672, CYSH_THIRO;  B7VI86, CYSH_VIBA3;  
A5F3I6, CYSH_VIBC3;  A7MSZ6, CYSH_VIBCB;  Q9KUX2, CYSH_VIBCH;  
C3LRB8, CYSH_VIBCM;  Q87L92, CYSH_VIBPA;  Q8CWK6, CYSH_VIBVU;  
Q7MHA7, CYSH_VIBVY;  Q8PHC7, CYSH_XANAC;  Q3BPY3, CYSH_XANC5;  
Q4UY09, CYSH_XANC8;  B0RPG5, CYSH_XANCB;  Q8P607, CYSH_XANCP;  
Q2P0H1, CYSH_XANOM;  B2SI06, CYSH_XANOP;  B2IA30, CYSH_XYLF2;  
Q9PD82, CYSH_XYLFA;  B0U6V9, CYSH_XYLFM;  Q87DH1, CYSH_XYLFT;  
A1JJS4, CYSH_YERE8;  A7FLY8, CYSH_YERP3;  B2K567, CYSH_YERPB;  
Q66ED2, CYSH_YERPS;  B1JJG7, CYSH_YERPY;  Q5NRM3, CYSH_ZYMMO;  
P56859, MET16_EMENI;  Q10270, MET16_SCHPO;  P18408, MET16_YEAST;  

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