ID 1.8.98.6 DE formate:CoB-CoM heterodisulfide,ferredoxin reductase. CA 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] = CA coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]- CA [ferredoxin]. CC -!- The enzyme is found in formate-oxidizing CO2-reducing methanogenic CC archaea such as Methanococcus maripaludis. CC -!- It consists of a cytoplasmic complex of HdrABC reductase and formate CC dehydrogenase. CC -!- Electron pairs donated by formate dehydrogenase are transferred to CC the HdrA subunit of the reductase, where they are bifurcated, CC reducing both ferredoxin and CoB-CoM heterodisulfide. cf. EC 1.8.7.3, CC EC 1.8.98.4, EC 1.8.98.5, and EC 1.8.98.1. DR Q6LWL2, HDRA_METMP ; Q6LY38, HDRB1_METMP; Q6LYD8, HDRB2_METMP; DR Q6LY39, HDRC1_METMP; Q6LYD7, HDRC2_METMP; //