ENZYME entry: EC 2.1.1.100
Accepted Name |
protein-S-isoprenylcysteine O-methyltransferase.
|
Alternative Name(s) |
isoprenylcysteine carboxylmethyltransferase. |
prenylated protein carboxyl methyltransferase. |
prenylcysteine carboxyl methyltransferase. |
Reaction catalysed |
[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine <=> [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine |
Comment(s) |
- C-terminal S-geranylgeranylcysteine and S-geranylcysteine residues
are also methylated, more slowly.
- Formerly EC 2.1.1.24.
|
Cross-references |
BRENDA | 2.1.1.100 |
EC2PDB | 2.1.1.100 |
ExplorEnz | 2.1.1.100 |
PRIAM enzyme-specific profiles | 2.1.1.100 |
KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.100 |
IUBMB Enzyme Nomenclature | 2.1.1.100 |
IntEnz | 2.1.1.100 |
MEDLINE | Find literature relating to 2.1.1.100 |
MetaCyc | 2.1.1.100 |
Rhea expert-curated reactions | 2.1.1.100 |
UniProtKB/Swiss-Prot |
Q9FMW9, ICMTA_ARATH; | Q93W54, ICMTB_ARATH; | Q558K8, ICMT_DICDI; |
O60725, ICMT_HUMAN; | Q8TMG0, ICMT_METAC; | Q9EQK7, ICMT_MOUSE; |
A2XX73, ICMT_ORYSI; | Q7XSR9, ICMT_ORYSJ; | Q9WVM4, ICMT_RAT; |
D6WJ77, ICMT_TRICA; | O12947, ICMT_XENLA; | P87014, MAM4_SCHPO; |
P32584, STE14_YEAST; |
|
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UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
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