ID 2.1.1.118 DE columbamine O-methyltransferase. CA columbamine + S-adenosyl-L-methionine = palmatine + S-adenosyl-L- CA homocysteine + H(+). CC -!- The product of this reaction is a protoberberine alkaloid that is CC widely distributed in the plant kingdom. CC -!- Distinct in specificity from EC 2.1.1.88. DR Q8H9A8, COOMT_COPJA; //