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ENZYME

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ENZYME entry: EC 2.1.1.122

Accepted Name
(S)-tetrahydroprotoberberine N-methyltransferase
Alternative Name(s)
tetrahydroprotoberberine cis-N-methyltransferase
Reaction catalysed
an (S)-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-methionine = an (S)-cis-N-methyl-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-homocysteine
Comment(s)
  • Involved in the biosynthesis of isoquinoline alkaloids in plants.
  • Substrates include (S)-canadine, (S)-stylopine, and (S)- tetrahydropalmatine.
Cross-references
BRENDA2.1.1.122
EC2PDB2.1.1.122
ExplorEnz2.1.1.122
PRIAM enzyme-specific profiles2.1.1.122
KEGG Ligand Database for Enzyme Nomenclature2.1.1.122
IUBMB Enzyme Nomenclature2.1.1.122
IntEnz2.1.1.122
MEDLINEFind literature relating to 2.1.1.122
MetaCyc2.1.1.122
Rhea expert-curated reactions2.1.1.122
UniProtKB/Swiss-Prot
D4N501, DIOX2_PAPSOC3SBS8, TNMT_ESCCAQ108P1, TNMT_PAPSO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
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