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ENZYME

ENZYME entry: EC 2.1.1.144

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.144
Accepted Name
trans-aconitate 2-methyltransferase
Reaction catalysed
trans-aconitate + S-adenosyl-L-methionine = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine
Comment(s)
  • Also catalyzes the formation of the methyl monoester of cis- aconitate, isocitrate and citrate, but more slowly.
  • While the enzyme from Escherichia coli forms (E)-3-(methoxycarbonyl)- pent-2-enedioate as the product, that from Saccharomyces cerevisiae forms (E)-2-(methoxycarbonylmethyl)butenedioate and is therefore classified as a separate enzyme (cf. EC 2.1.1.145).
Cross-references
BRENDA2.1.1.144
EC2PDB2.1.1.144
ExplorEnz2.1.1.144
KEGG Ligand Database for Enzyme Nomenclature2.1.1.144
IUBMB Enzyme Nomenclature2.1.1.144
MEDLINEFind literature relating to 2.1.1.144
MetaCyc2.1.1.144
Rhea expert-curated reactions2.1.1.144
UniProtKB/Swiss-Prot
B9MBN9, TAM_ACIETA1W9K6, TAM_ACISJB6JIA0, TAM_AFIC5
Q8UH15, TAM_AGRFCA1K8U5, TAM_AZOSBA6WZN1, TAM_BRUA4
A9M6C1, TAM_BRUC2Q8YI91, TAM_BRUMEA5VRJ7, TAM_BRUO2
B0CHP1, TAM_BRUSIQ8FZM5, TAM_BRUSUQ9RX93, TAM_DEIRA
A9BVK1, TAM_DELASA7ZLX5, TAM_ECO24B7URP6, TAM_ECO27
B7MMY3, TAM_ECO45B7L7L9, TAM_ECO55Q8XAZ2, TAM_ECO57
B5Z1X6, TAM_ECO5EB7NIJ1, TAM_ECO7IB7LZC1, TAM_ECO8A
C4ZWT6, TAM_ECOBWB1XEA7, TAM_ECODHA8A072, TAM_ECOHS
A1AB99, TAM_ECOK1Q0THR9, TAM_ECOL5Q8FHF2, TAM_ECOL6
B1IRU1, TAM_ECOLCP76145, TAM_ECOLIB7N4U4, TAM_ECOLU
B6IAS2, TAM_ECOSEB1LF96, TAM_ECOSMQ1RBP8, TAM_ECOUT
A4WAG4, TAM_ENT38B7LRD2, TAM_ESCF3B5XQT8, TAM_KLEV3
B8ISV4, TAM_METNOB1LXF6, TAM_METRJB0UPF4, TAM_METS4
A0QM44, TAM_MYCA1P66886, TAM_MYCBOA1KFB7, TAM_MYCBP
C1AJX2, TAM_MYCBTA4T0W0, TAM_MYCGIB2HNX5, TAM_MYCMM
A3PTG0, TAM_MYCSJA1U9V4, TAM_MYCSKQ1BF27, TAM_MYCSS
A5TZ21, TAM_MYCTAP9WGA2, TAM_MYCTOP9WGA3, TAM_MYCTU
A0PN72, TAM_MYCUAA1T273, TAM_MYCVPQ1QJC0, TAM_NITHX
Q3SPQ7, TAM_NITWNA1TP97, TAM_PARC0Q02N15, TAM_PSEAB
Q9I0S1, TAM_PSEAEA6V4P3, TAM_PSEP7B3PTJ5, TAM_RHIE6
Q2KAZ5, TAM_RHIECQ98K73, TAM_RHILOB5ZUL2, TAM_RHILW
Q92RC5, TAM_RHIMEB9JBE6, TAM_RHIR8Q0SED2, TAM_RHOJR
Q2IYT0, TAM_RHOP2Q07PZ6, TAM_RHOP5Q6N3T8, TAM_RHOPA
Q216J6, TAM_RHOPBQ133R5, TAM_RHOPSB3QFV9, TAM_RHOPT
Q32G05, TAM_SHIDSQ0T4L2, TAM_SHIF8Q83RE0, TAM_SHIFL
C3M8G8, TAM_SINFNA6U707, TAM_SINMWQ82HD9, TAM_STRAW
Q9K3T2, TAM_STRCOC5CSI6, TAM_VARPSA1JU33, TAM_YERE8
A7FGU8, TAM_YERP3Q1C6F5, TAM_YERPAB2K7X9, TAM_YERPB
Q8ZDP7, TAM_YERPEA9R6H5, TAM_YERPGQ1CHU7, TAM_YERPN
A4TLZ2, TAM_YERPPQ669E2, TAM_YERPSB1JHA2, TAM_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-