ENZYME entry: EC 2.1.1.160
Accepted Name |
caffeine synthase.
|
Alternative Name(s) |
3N-methyltransferase. |
dimethylxanthine methyltransferase. |
Reaction catalysed |
- S-adenosyl-L-methionine + theobromine <=> caffeine + H(+) + S-adenosyl-L-homocysteine
- 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> caffeine + H(+) + S-adenosyl-L-homocysteine
- 7-methylxanthine + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + theobromine
|
Comment(s) |
Paraxanthine is the best substrate for this enzyme but the
paraxanthine pathway is considered to be a minor pathway for caffeine
biosynthesis.
|
Cross-references |
BRENDA | 2.1.1.160 |
EC2PDB | 2.1.1.160 |
ExplorEnz | 2.1.1.160 |
PRIAM enzyme-specific profiles | 2.1.1.160 |
KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.160 |
IUBMB Enzyme Nomenclature | 2.1.1.160 |
IntEnz | 2.1.1.160 |
MEDLINE | Find literature relating to 2.1.1.160 |
MetaCyc | 2.1.1.160 |
Rhea expert-curated reactions | 2.1.1.160 |
UniProtKB/Swiss-Prot |
|
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