ENZYME entry: EC 2.1.1.164
Accepted Name |
Demethylrebeccamycin-D-glucose O-methyltransferase.
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Reaction catalysed |
4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> rebeccamycin + S-adenosyl-L-homocysteine |
Comment(s) |
- Catalyzes the last step in the biosynthesis of rebeccamycin,
an indolocarbazole alkaloid produced by the bacterium Lechevalieria
aerocolonigenes.
- The enzyme is able to use a wide variety substrates, tolerating
variation on the imide heterocycle, deoxygenation of the sugar
moiety, and even indolocarbazole glycoside anomers.
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Cross-references |
BRENDA | 2.1.1.164 |
EC2PDB | 2.1.1.164 |
ExplorEnz | 2.1.1.164 |
PRIAM enzyme-specific profiles | 2.1.1.164 |
KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.164 |
IUBMB Enzyme Nomenclature | 2.1.1.164 |
IntEnz | 2.1.1.164 |
MEDLINE | Find literature relating to 2.1.1.164 |
MetaCyc | 2.1.1.164 |
Rhea expert-curated reactions | 2.1.1.164 |
UniProtKB/Swiss-Prot |
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