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ENZYME

ENZYME entry: EC 2.1.1.166

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.166
Accepted Name
23S rRNA (uridine(2552)-2'-O)-methyltransferase
Alternative Name(s)
FTSJ
Um(2552) 23S ribosomal RNA methyltransferase
Um2552 methyltransferase
Reaction catalysed
uridine(2552) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methyluridine(2552) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)
Comment(s)
The enzyme catalyzes the 2'-O-methylation of the universally conserved U2552 in the A loop of 23S rRNA.
Cross-references
BRENDA2.1.1.166
EC2PDB2.1.1.166
ExplorEnz2.1.1.166
KEGG Ligand Database for Enzyme Nomenclature2.1.1.166
IUBMB Enzyme Nomenclature2.1.1.166
MEDLINEFind literature relating to 2.1.1.166
MetaCyc2.1.1.166
Rhea expert-curated reactions2.1.1.166
UniProtKB/Swiss-Prot
Q6F8N1, RLME_ACIADB7GY18, RLME_ACIB3B7I636, RLME_ACIB5
B2HXD3, RLME_ACIBCB0VSM4, RLME_ACIBSA3M851, RLME_ACIBT
B0VEE9, RLME_ACIBYA5G029, RLME_ACICJB7J8G6, RLME_ACIF2
B5ENR5, RLME_ACIF5A1W8H0, RLME_ACISJA3MZW0, RLME_ACTP2
B3H123, RLME_ACTP7B0BUF3, RLME_ACTPJA6VPC2, RLME_ACTSZ
A0KNF1, RLME_AERHHA4SJQ7, RLME_AERS4B6JHM9, RLME_AFIC5
Q8UHR0, RLME_AGRFCQ21WW8, RLME_ALBFTQ0VSS9, RLME_ALCBS
Q5E7M3, RLME_ALIF1B5FA72, RLME_ALIFMB6END5, RLME_ALISL
Q0A769, RLME_ALKEHB9JSD2, RLME_ALLAMQ2IPT3, RLME_ANADE
A7H9A5, RLME_ANADFB9KIP4, RLME_ANAMFQ5PAN0, RLME_ANAMM
Q2GKK2, RLME_ANAPZO28228, RLME_ARCFUQ5P1G0, RLME_AROAE
A8II77, RLME_AZOC5A1K598, RLME_AZOSBC1DFL6, RLME_AZOVD
A1URN3, RLME_BARBKQ6G4Z3, RLME_BARHEQ6G0S9, RLME_BARQU
A9IMA1, RLME_BART1Q1LSK2, RLME_BAUCHQ6MN40, RLME_BDEBA
Q7VQM8, RLME_BLOFLQ493U3, RLME_BLOPBQ2KVR5, RLME_BORA1
Q0SNJ8, RLME_BORAPQ7WMD3, RLME_BORBRO51293, RLME_BORBU
B7J1P0, RLME_BORBZB5RLD9, RLME_BORDLQ661V2, RLME_BORGP
Q7W8R6, RLME_BORPAA9HYV0, RLME_BORPDQ7VZ56, RLME_BORPE
B5RRD2, RLME_BORRAQ89N72, RLME_BRADUC0QX75, RLME_BRAHW
A5EHP2, RLME_BRASBA4YSS3, RLME_BRASOB2SAY0, RLME_BRUA1
Q2YKU4, RLME_BRUA2A6X5L4, RLME_BRUA4Q578H4, RLME_BRUAB
A9MBW8, RLME_BRUC2C0RLJ5, RLME_BRUMBQ8YCD5, RLME_BRUME
A5VUZ8, RLME_BRUO2A9WYY2, RLME_BRUSIQ8FVY1, RLME_BRUSU
P57463, RLME_BUCAIQ8K9G7, RLME_BUCAPQ89AF1, RLME_BUCBP
Q057J5, RLME_BUCCCB1YMW2, RLME_BURA4A0K6C1, RLME_BURCH
B4E5F3, RLME_BURCJQ0BGJ2, RLME_BURCMQ39HN2, RLME_BURL3
A9ACL8, RLME_BURM1A3MIQ3, RLME_BURM7A2S3Q7, RLME_BURM9
Q62L80, RLME_BURMAA1V319, RLME_BURMSB1JZE9, RLME_BURO0
Q1BXD0, RLME_BURO1A3NTW3, RLME_BURP0Q3JTT5, RLME_BURP1
A3N853, RLME_BURP6Q63V86, RLME_BURPSQ2SUW0, RLME_BURTA
A4JDA6, RLME_BURVGB0T8J6, RLME_CAUSKQ9A7V4, RLME_CAUVC
B3PLQ4, RLME_CELJUA0RV28, RLME_CENSYA3PJK8, RLME_CERS1
Q3J2Q5, RLME_CERS4Q11L51, RLME_CHESBQ1QSY2, RLME_CHRI1
Q7NRI3, RLME_CHRVOA8AQ68, RLME_CITK8Q47YJ3, RLME_COLP3
B6J802, RLME_COXB1B6IZD5, RLME_COXB2A9KGE6, RLME_COXBN
A9N8M5, RLME_COXBRQ83BY4, RLME_COXBUA7MIM8, RLME_CROS8
Q1LLA8, RLME_CUPMCQ0K8Y4, RLME_CUPNHQ46Z98, RLME_CUPPJ
B3R1S2, RLME_CUPTRQ47HI2, RLME_DECARA9BML0, RLME_DELAS
C0QGP2, RLME_DESAHB8FL12, RLME_DESALA8ZT18, RLME_DESOH
Q6AJ42, RLME_DESPSA5EXB6, RLME_DICNVA7ZS75, RLME_ECO24
B7UJ72, RLME_ECO27B7MBU8, RLME_ECO45B7LHP2, RLME_ECO55
P0C0R8, RLME_ECO57B5YS68, RLME_ECO5EB7NKP6, RLME_ECO7I
B7N363, RLME_ECO81B7M085, RLME_ECO8AC4ZSR8, RLME_ECOBW
B1XGY9, RLME_ECODHA8A4Z3, RLME_ECOHSA1AG82, RLME_ECOK1
Q0TCT1, RLME_ECOL5P0C0R9, RLME_ECOL6B1IQU4, RLME_ECOLC
P0C0R7, RLME_ECOLIB7NDG3, RLME_ECOLUB6I1Q2, RLME_ECOSE
B1LFS9, RLME_ECOSMQ1R6F9, RLME_ECOUTA4XYE8, RLME_ECTM1
C5BFB0, RLME_EDWI9Q3YRW8, RLME_EHRCJQ2GGT6, RLME_EHRCR
Q5FH15, RLME_EHRRGQ5FEH6, RLME_EHRRWQ2GDL7, RLME_EHRS3
A4WEZ0, RLME_ENT38B2VGT0, RLME_ERWT9Q2N843, RLME_ERYLH
B7LR46, RLME_ESCF3B0TZQ8, RLME_FRAP2Q14HT5, RLME_FRAT1
A7NAC9, RLME_FRATFQ2A4Z7, RLME_FRATHB2SF85, RLME_FRATM
A0Q526, RLME_FRATNQ0BNB8, RLME_FRATOQ5NGD3, RLME_FRATT
A4IYP4, RLME_FRATWB8F4C0, RLME_GLAP5Q5FNQ1, RLME_GLUOX
Q0BT08, RLME_GRABCQ7VLF2, RLME_HAEDUQ4QKJ2, RLME_HAEI8
P45162, RLME_HAEINQ2SMM1, RLME_HAHCHA1WXX3, RLME_HALHL
B9LSX2, RLME_HALLTQ5UYP9, RLME_HALMAB0R7G3, RLME_HALS3
Q9HN40, RLME_HALSAQ18E61, RLME_HALWDC4K7K8, RLME_HAMD5
A4G4B0, RLME_HERARQ0I2R1, RLME_HISS1Q31HG6, RLME_HYDCU
Q0C187, RLME_HYPNAQ5QXK8, RLME_IDILOA6T081, RLME_JANMA
Q28QW4, RLME_JANSCA6TEJ8, RLME_KLEP7B5XSW2, RLME_KLEV3
Q1MRQ0, RLME_LAWIPQ5X1A0, RLME_LEGPAA5IHX0, RLME_LEGPC
Q5ZRT1, RLME_LEGPHQ5WT13, RLME_LEGPLB1XXG3, RLME_LEPCP
A0LC14, RLME_MAGMMQ65TZ0, RLME_MANSMQ0AQH3, RLME_MARMM
A1TXM4, RLME_MARN8C6C068, RLME_MARSDA6UUK5, RLME_META3
Q8TR92, RLME_METACQ0W1F9, RLME_METARA7I848, RLME_METB6
Q466Q1, RLME_METBFQ12WR3, RLME_METBUQ607B2, RLME_METCA
Q1H387, RLME_METFKQ2FNX6, RLME_METHJQ58771, RLME_METJA
A2SSW7, RLME_METLZA4FYM2, RLME_METM5A9A6B9, RLME_METM6
A6VJR0, RLME_METM7Q8PUP4, RLME_METMAA3CVJ3, RLME_METMJ
Q6LZL8, RLME_METMPB8GG79, RLME_METPEA2SF90, RLME_METPP
A5UKI5, RLME_METS3Q2NHD6, RLME_METSTO27801, RLME_METTH
A0B8A1, RLME_METTPA6USA0, RLME_METVSQ1D841, RLME_MYXXD
Q3IT24, RLME_NATPDQ5F9L0, RLME_NEIG1B4RK82, RLME_NEIG2
A9M3N1, RLME_NEIM0Q9JQX5, RLME_NEIMAQ7DDL2, RLME_NEIMB
A1KT57, RLME_NEIMFQ0AHC6, RLME_NITECQ820A2, RLME_NITEU
Q1QKB6, RLME_NITHXA9A3M9, RLME_NITMSQ2YBT1, RLME_NITMU
Q3J823, RLME_NITOCQ729T9, RLME_NITV2A1VC40, RLME_NITV4
B8DNJ4, RLME_NITV9Q3SQN7, RLME_NITWNQ2GB53, RLME_NOVAD
Q30YX3, RLME_OLEA2A1TQF0, RLME_PARC0A1B962, RLME_PARDP
A7HSA5, RLME_PARL1Q2W0P2, RLME_PARM1B2JFN9, RLME_PARP8
B2SZR9, RLME_PARPJQ13W47, RLME_PARXLQ9CNJ3, RLME_PASMU
Q6D9B9, RLME_PECASC6DKI3, RLME_PECCPQ4FMX1, RLME_PELUB
Q7MYY0, RLME_PHOLLQ6LUJ9, RLME_PHOPRQ6L1E2, RLME_PICTO
A4SXL6, RLME_POLAQA1VQI6, RLME_POLNAQ129M4, RLME_POLSJ
B4F2B2, RLME_PROMHQ48E69, RLME_PSE14Q15VJ6, RLME_PSEA6
B7V1G4, RLME_PSEA8Q02FS0, RLME_PSEABP95454, RLME_PSEAE
Q1IF51, RLME_PSEE4Q4KIG3, RLME_PSEF5C3K267, RLME_PSEFS
A5W995, RLME_PSEP1A6VCK9, RLME_PSEP7Q3KI92, RLME_PSEPF
B0KHY6, RLME_PSEPGQ88DV0, RLME_PSEPKB1J262, RLME_PSEPW
Q87WP7, RLME_PSESMQ3IE64, RLME_PSET1Q4ZNQ4, RLME_PSEU2
Q4FQX1, RLME_PSYA2Q1Q955, RLME_PSYCKA1ST38, RLME_PSYIN
A5WCU8, RLME_PSYWFQ8XZ79, RLME_RALN1B2UGQ0, RLME_RALPJ
B3PQL4, RLME_RHIE6Q2KC36, RLME_RHIECQ1ML15, RLME_RHIJ3
Q983F8, RLME_RHILOB5ZR94, RLME_RHILWQ92RT9, RLME_RHIME
B9J9U0, RLME_RHIR8A5VFI9, RLME_RHIWRQ2IV68, RLME_RHOP2
Q07LH9, RLME_RHOP5Q6N7Q9, RLME_RHOPAQ212R3, RLME_RHOPB
Q138J5, RLME_RHOPSB3QFD2, RLME_RHOPTQ2RXU5, RLME_RHORT
C3PMK3, RLME_RICAEA8GMD3, RLME_RICAHA8GV60, RLME_RICB8
Q1RHG3, RLME_RICBRA8EXN1, RLME_RICCKQ92J64, RLME_RICCN
Q4UKG2, RLME_RICFEQ9ZE00, RLME_RICPRC4K0Q4, RLME_RICPU
B0BWD8, RLME_RICROA8GQZ0, RLME_RICRSQ68XK5, RLME_RICTY
Q164M8, RLME_ROSDOQ5LSB0, RLME_RUEPOQ1GHF1, RLME_RUEST
A1AW32, RLME_RUTMCQ21H48, RLME_SACD2B5F6U7, RLME_SALA4
A9MP28, RLME_SALARQ57JH1, RLME_SALCHB5FI23, RLME_SALDC
B5R0H0, RLME_SALEPB5REP5, RLME_SALG2B4TJ16, RLME_SALHS
B4T708, RLME_SALNSQ5PLC1, RLME_SALPAA9N744, RLME_SALPB
C0PZ62, RLME_SALPCB5BGK3, RLME_SALPKB4TWE7, RLME_SALSV
Q8Z3H3, RLME_SALTIQ8ZLS7, RLME_SALTYA8G900, RLME_SERP5
A1S454, RLME_SHEAMB8E6M4, RLME_SHEB2A3D7L4, RLME_SHEB5
A6WRH7, RLME_SHEB8A9KZX9, RLME_SHEB9Q12QI9, RLME_SHEDO
Q086I0, RLME_SHEFNB0TQB0, RLME_SHEHHA3QGV3, RLME_SHELP
Q8EHM3, RLME_SHEONA8H748, RLME_SHEPAA4Y9C8, RLME_SHEPC
B8CKG5, RLME_SHEPWA0KTY8, RLME_SHESAA8FYS8, RLME_SHESH
Q0HLG9, RLME_SHESMQ0HXS3, RLME_SHESRA1RGW7, RLME_SHESW
B1KRR8, RLME_SHEWMB2U1Z8, RLME_SHIB3Q31W56, RLME_SHIBS
Q32BF4, RLME_SHIDSQ0T0A5, RLME_SHIF8P0C0S0, RLME_SHIFL
Q3YX62, RLME_SHISSC3MGQ4, RLME_SINFNA6U6F0, RLME_SINMW
Q2NW30, RLME_SODGMA9FQE4, RLME_SORC5Q1GPG3, RLME_SPHAL
B4SRA0, RLME_STRM5B2FKA1, RLME_STRMKA4VNP3, RLME_STUS1
A0LGZ0, RLME_SYNFMQ9HIH4, RLME_THEACQ97C13, RLME_THEVO
Q3SJR5, RLME_THIDAB8GNX9, RLME_THISHC4L8Y1, RLME_TOLAT
Q73L97, RLME_TREDEO83687, RLME_TREPAQ8KTR0, RLME_TREPR
B2S3S1, RLME_TREPSC5CKU4, RLME_VARPSA1WEE7, RLME_VEREI
A5CX75, RLME_VESOHB7VJI4, RLME_VIBA3A7MZH4, RLME_VIBC1
A5F937, RLME_VIBC3Q9KU87, RLME_VIBCHC3LSP1, RLME_VIBCM
Q87LZ4, RLME_VIBPAQ8DBW7, RLME_VIBVUQ7MI01, RLME_VIBVY
Q8D2X0, RLME_WIGBRQ73IS9, RLME_WOLPMQ5GS59, RLME_WOLTR
Q8PLQ8, RLME_XANACQ4UTQ4, RLME_XANC8B0RTZ3, RLME_XANCB
Q8P9Y1, RLME_XANCPQ3BUR8, RLME_XANE5Q2P1M0, RLME_XANOM
B2SUB8, RLME_XANOPQ5GYL7, RLME_XANORA7IDJ5, RLME_XANP2
B2I696, RLME_XYLF2Q9PH52, RLME_XYLFAB0U1F2, RLME_XYLFM
Q87F66, RLME_XYLFTA1JIW2, RLME_YERE8A7FMS9, RLME_YERP3
Q1CC00, RLME_YERPAB2K2P8, RLME_YERPBQ8ZBB5, RLME_YERPE
Q1CEK6, RLME_YERPNA4TRJ0, RLME_YERPPQ66F67, RLME_YERPS
B1JMH7, RLME_YERPYQ5NQH8, RLME_ZYMMO

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