ID   2.1.1.167
DE   27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase.
CA   guanosine(2922) in 27S pre-rRNA + S-adenosyl-L-methionine = 2'-O-
CA   methylguanosine(2922) in 27S pre-rRNA + H(+) + S-adenosyl-L-homocysteine.
CC   -!- Spb1p is a site-specific 2'-O-ribose RNA methyltransferase that
CC       catalyzes the formation of 2'-O-methylguanosine(2922), a universally
CC       conserved position of the catalytic center of the ribosome that is
CC       essential for translation.
CC   -!- 2'-O-methylguanosine(2922) is formed at a later stage of the
CC       processing, during the maturation of of the 27S pre-rRNA.
CC   -!- In absence of snR52, Spb1p can also catalyze the formation of
CC       uridine(2921).
DR   P25582, SPB1_YEAST ;
//