ENZYME entry: EC 2.1.1.174

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.174

Accepted Name

23S rRNA (guanine(1835)-N(2))-methyltransferase

Alternative Name(s)

ribosomal RNA large subunit methyltransferase G

Reaction catalysed

guanosine(1835) in 23S rRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)

Comment(s)

The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.
The enzyme specifically methylates guanine(1835) at N(2) in 23S rRNA.
Formerly EC 2.1.1.52.

Cross-references

BRENDA

2.1.1.174

EC2PDB

2.1.1.174

ExplorEnz

2.1.1.174

KEGG Ligand Database for Enzyme Nomenclature

2.1.1.174

IUBMB Enzyme Nomenclature

2.1.1.174

MEDLINE

Find literature relating to 2.1.1.174

MetaCyc

2.1.1.174

Rhea expert-curated reactions

2.1.1.174

UniProtKB/Swiss-Prot

A0KHC4, RLMG_AERHH	A4SQM2, RLMG_AERS4	Q0VPK2, RLMG_ALCBS
Q5E6X8, RLMG_ALIF1	B5FBH8, RLMG_ALIFM	B6EIC1, RLMG_ALISL
B4RZB4, RLMG_ALTMD	A8APY0, RLMG_CITK8	Q488Q3, RLMG_COLP3
A7MIS8, RLMG_CROS8	A7ZRW7, RLMG_ECO24	Q8XAK8, RLMG_ECO57
B5YRC4, RLMG_ECO5E	B1XG88, RLMG_ECODH	A8A4P1, RLMG_ECOHS
A1AG02, RLMG_ECOK1	Q0TD22, RLMG_ECOL5	Q8FDE5, RLMG_ECOL6
B1IRN3, RLMG_ECOLC	P42596, RLMG_ECOLI	B1LFI2, RLMG_ECOSM
Q1R6P6, RLMG_ECOUT	A4XQA3, RLMG_ECTM1	A4WER8, RLMG_ENT38
B2VDD5, RLMG_ERWT9	A6TEC2, RLMG_KLEP7	B5XTX7, RLMG_KLEV3
A0L9S5, RLMG_MAGMM	Q6D9G1, RLMG_PECAS	Q6LTZ3, RLMG_PHOPR
Q48DT7, RLMG_PSE14	Q15YR1, RLMG_PSEA6	Q02G60, RLMG_PSEAB
Q9HVH4, RLMG_PSEAE	Q1I4K4, RLMG_PSEE4	Q4K5Q4, RLMG_PSEF5
A5W920, RLMG_PSEP1	A6VC08, RLMG_PSEP7	Q3K6H7, RLMG_PSEPF
B0KHQ8, RLMG_PSEPG	Q88E20, RLMG_PSEPK	B1J2W7, RLMG_PSEPW
Q0EDR2, RLMG_PSESH	Q87WA9, RLMG_PSESM	Q3IHQ6, RLMG_PSET1
Q4ZNG3, RLMG_PSEU2	A1SX22, RLMG_PSYIN	B5F6B6, RLMG_SALA4
A9MPU2, RLMG_SALAR	Q57JN9, RLMG_SALCH	B5FHV5, RLMG_SALDC
B5QZ55, RLMG_SALEP	B5REH7, RLMG_SALG2	B4TIU8, RLMG_SALHS
B4T690, RLMG_SALNS	Q5PC93, RLMG_SALPA	A9N601, RLMG_SALPB
B5BG31, RLMG_SALPK	B4TVV4, RLMG_SALSV	Q8Z3L8, RLMG_SALTI
Q8ZLX5, RLMG_SALTY	A8GJW6, RLMG_SERP5	A1S8P4, RLMG_SHEAM
A3D130, RLMG_SHEB5	A6WRY2, RLMG_SHEB8	A9L0V0, RLMG_SHEB9
Q12K11, RLMG_SHEDO	Q07YH6, RLMG_SHEFN	B0TR07, RLMG_SHEHH
A3QH04, RLMG_SHELP	Q8EHW5, RLMG_SHEON	A8H786, RLMG_SHEPA
A4Y3Y0, RLMG_SHEPC	A0KTP8, RLMG_SHESA	A8FYW7, RLMG_SHESH
Q0HLQ7, RLMG_SHESM	Q0HY38, RLMG_SHESR	A1RN12, RLMG_SHESW
B1KD54, RLMG_SHEWM	B2U1T3, RLMG_SHIB3	Q31WU9, RLMG_SHIBS
Q32BN8, RLMG_SHIDS	Q0T0I4, RLMG_SHIF8	Q821A5, RLMG_SHIFL
Q3YXQ6, RLMG_SHISS	Q82N59, RLMG_STRAW	Q9K3L9, RLMG_STRCO
B1VMX8, RLMG_STRGG	A4VI28, RLMG_STUS1	B7VKD0, RLMG_VIBA3
A7N1U8, RLMG_VIBC1	A5F5X3, RLMG_VIBC3	Q9KPR9, RLMG_VIBCH
Q87MA4, RLMG_VIBPA	Q8DBJ8, RLMG_VIBVU	Q7MIC5, RLMG_VIBVY
A1JR10, RLMG_YERE8	A7FE15, RLMG_YERP3	Q1C310, RLMG_YERPA
B2K3B8, RLMG_YERPB	Q0WJ78, RLMG_YERPE	A9R1N3, RLMG_YERPG
Q1CMJ1, RLMG_YERPN	A4THM8, RLMG_YERPP	Q665P6, RLMG_YERPS
B1JLA4, RLMG_YERPY

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.

All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-