ENZYME entry: EC 2.1.1.180
| Accepted Name | |||||
|---|---|---|---|---|---|
| 16S rRNA (adenine(1408)-N(1))-methyltransferase | |||||
| Reaction catalysed | |||||
| adenosine(1408) in 16S rRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(1408) in 16S rRNA + S-adenosyl-L-homocysteine + H(+) | |||||
| Comment(s) | |||||
| The enzyme provides a panaminoglycoside-resistant nature through interference with the binding of aminoglycosides toward the A site of 16S rRNA through N(1)-methylation at position adenine(1408). | |||||
| Cross-references | |||||
| BRENDA | 2.1.1.180 | ||||
| EC2PDB | 2.1.1.180 | ||||
| ExplorEnz | 2.1.1.180 | ||||
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.180 | ||||
| IUBMB Enzyme Nomenclature | 2.1.1.180 | ||||
| MEDLINE | Find literature relating to 2.1.1.180 | ||||
| MetaCyc | 2.1.1.180 | ||||
| Rhea expert-curated reactions | 2.1.1.180 | ||||
| UniProtKB/Swiss-Prot |
| ||||
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