ENZYME entry: EC 2.1.1.180
Accepted Name |
16S rRNA (adenine(1408)-N(1))-methyltransferase.
|
Reaction catalysed |
adenosine(1408) in 16S rRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methyladenosine(1408) in 16S rRNA + S-adenosyl-L-homocysteine |
Comment(s) |
The enzyme provides a panaminoglycoside-resistant nature through
interference with the binding of aminoglycosides toward the A site of
16S rRNA through N(1)-methylation at position adenine(1408).
|
Cross-references |
BRENDA | 2.1.1.180 |
EC2PDB | 2.1.1.180 |
ExplorEnz | 2.1.1.180 |
PRIAM enzyme-specific profiles | 2.1.1.180 |
KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.180 |
IUBMB Enzyme Nomenclature | 2.1.1.180 |
IntEnz | 2.1.1.180 |
MEDLINE | Find literature relating to 2.1.1.180 |
MetaCyc | 2.1.1.180 |
Rhea expert-curated reactions | 2.1.1.180 |
UniProtKB/Swiss-Prot |
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