ENZYME entry: EC 2.1.1.180
| Accepted Name |
|---|
| 16S rRNA (adenine(1408)-N(1))-methyltransferase.
|
| Reaction catalysed |
|---|
| S-adenosyl-L-methionine + adenine(1408) in 16S rRNA <=> S-adenosyl-L-homocysteine + N(1)-methyladenine(1408) in 16S rRNA |
| Comment(s) |
|---|
| The enzyme provides a panaminoglycoside-resistant nature through
interference with the binding of aminoglycosides toward the A site of
16S rRNA through N(1)-methylation at position adenine(1408).
|
| Cross-references |
|---|
| BRENDA | 2.1.1.180 |
| EC2PDB | 2.1.1.180 |
| ExplorEnz | 2.1.1.180 |
| PRIAM enzyme-specific profiles | 2.1.1.180 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.180 |
| IUBMB Enzyme Nomenclature | 2.1.1.180 |
| IntEnz | 2.1.1.180 |
| MEDLINE | Find literature relating to 2.1.1.180 |
| MetaCyc | 2.1.1.180 |
| UniProtKB/Swiss-Prot |
|
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